Inositol is a naturally occurring isomer of glucose. Inositol works by playing a supporting role in cellular communication by relaying messages from serotonin and norepinephrine receptors.

Preliminary evidence suggests that taking high-dose inositol (12 grams/day) for four weeks may help reduce depression. Though people using inositol appear to relapse once inositol is discontinued, inositol may play an important role in helping those that need added short term support while they are rebalancing their neurotransmitter levels.